Saturday, August 31, 2019

Senior Nuts

Human beings are born with numerous natural instincts; yet, none is as basic as the instinct of survival. Though many people may never need it, it is an invaluable knowledge given to us by God. Humans are born to live and consequently they are born with the ability to survive. When we talk about ‘survival skills’ we consider ways in which we can fulfill our most urgent needs in any situation. Via many years of societal evolution, we have lost our ability to provide for ourselves if we don’t have access to a store, and have become ignorant on how to survive in the wilderness.If you can find food and water, and you can make fire and shelter, then you can survive in the wilderness. And when it comes time to find your way out of your situation, you will need to know how to navigate without a phone, gps, compass, or map. However, should you find yourself lacking one of these five components; you will not survive, or ecape, unless the void is compensated. It is a simple fact that if you do not eat then you will not live. However, finding food is much more complicated than it seems. The methods for finding and getting hold of wild food in a particular kind of country usually require detailed local knowledge† (Bridge 270). Unfortunately, when in a survival situation detailed knowledge of an area and its edible plants is not always an asset. In addition, it is rare for you to have a fishing pole or any kind of hunting equipment. Thus, you might find yourself literally up the creek without a paddle. However, there are a few ways to find food, and a few well-known plants that are edible. First of all, you must take advantage of your location.It can be difficult to catch animals on land thus you must find edible plants. Among the well-known edible plants are blackberries, black walnuts, cattail, daylily buds, hickory nuts, acorns, and morning glory leaves (Edible). However, it is often difficult to discern these edible plants from their poisonous peers. There is an edibility test you can use when faced with this situation. You must simply take a plant and rub it on a sensitive part of your body, the inside of the wrist for example, and wait fifteen minutes.If there isn't any adverse effect then you should chew a very small amount of the plant for five minutes and see if there is any adverse effect. If, after this, you still feel fine then swallow the plant and wait eight hours. If you are still feeling okay then eat a small handful and wait another eight hours. If nothing happens then it is okay for you to eat the plant sparingly. (Edibility Test) Some other tips for finding edible food include avoiding all plants with white sap, tiny hairs, umbrella shaped flowers and white or green berries.In addition, you should stay away from mushrooms and fungi, plants with bulb roots and fruits from plants with shiny leaves. Aggregate berries such as raspberries are always edible, as are single fruits on a stem. With this information y ou can find food and pass step one of surviving. However, it is very important that if a water source is not available you should not eat because water is required for digestion (Equipped). The second step to surviving is finding, or creating shelter. Exposure to extreme heat or cold can result in death from only three hours of exposure.Consequently, finding a shelter or constructing you out of the resources around you is vital. An example of this is when a married couple and their young child found themselves stranded in a snow bank. Before going out to seek help the man built his wife and child a cave in the snow. Without this cave, the man's family would have almost certainly died (Survival). Regardless of the scenario, a shelter is needed and should be constructed in a safe environment. You should avoid camping in meadows because of the mosquitoes and you should be cautious of animal shelters.Shelters can also be constructed out of tarps, tree branches, and snow. It is unfortuna te that humans have destroyed so much nature because we have made it harder for ourselves to survive by ruining trees, creating paths and destroying natural shelters. â€Å"It is rare than an overhanging rock that serves as a good shelter is even capable of being found these days† (Bridge 174). Perhaps the most important asset for survival is water. It would be a miracle if you survived for more than three days without water and there is no substitute for it. It is imperative that when driven by thirst you do not drink seawater, blood, or urine.These fluids will only hasten dehydration (Survival). In addition, you must know that thirst itself is not good indicator of hydration levels. You can be dehydrated and lack thirst. â€Å"Dark colored urine is the most reliable indication of significant dehydration† (Equipped). There are many ways to find water, but you should not push yourself too far. Rationing sweat is just as important as rationing water. You can find water by collecting dew or melting snow. You should avoid consuming un-melted snow because it lowers your body temperature. Follow animal tracks downhill; they might lead to a watering hole.Also, if you find yourself in an arid area, you should dig to find water. Even in a desert you can find water. Simply dig a hole in the sand, covering and suspending a plastic bag into it and collecting water, which condenses at the bottom of the plastic container. If bad comes to worse, you should not avoid drinking water that might be contaminated. Only do so as a last resort. An intestinal problem is much friendlier when contrasted with death (Equipped). For nearly every situation, fire will be the essence of your survival. Fire is the Swiss-army-knife of wilderness survival. It can play multiple roles.It provides warmth, and comfort, while cooking and preserving food. It also purifies water, signals for help, and provides protection from animals. †It can be a psychological boost by providing peace of mind, and companionship†. (FireCraft) To make a fire, you need to understand the mechanics of fire, and how it works. †Fuel ( in a nongaseous state)does not burn directly. † When heat is applied to the fuel, it creates a gas which, when mixed with air, burns. There are many types of fire structures, which can all be equally successful. The tepee style is the simplest, both to explain and to build.To make a tepee fire, you will arrange a tinder ball and stack small sticks around it in a cone shape. You will light it in the middle, causing the tinder ball to burn which catches the twigs on fire that then fall inward fueling the fire further. Once you are able and willing to escape the wilderness, you will need to figure out which way is north. An easy way of doing so is to create a make-shift compass rose on the ground. You can make this by sticking a leafless branch, which will cast a definite shadow, in the ground and marking the tip of the shadow, which g ives you the west heading.Wait for about fifteen minutes and mark the new point, giving you the east heading. Now stand with the west to your left and east to your right. You are now facing north. When on the move, be sure to leave yourself plenty of daylight to setup camp and to build a fire. With food, water, shelter and fire you can survive in the wilderness. Yet, in order to find these things you must try to maintain a positive mental attitude (Equipped). If you find yourself in a survival situation, you must prioritize: water then shelter then food. Never give up.As easy as giving up might seem when faced with death and lacking hope, you must keep on trying and you must think. Do not waste energy by doing before thinking. You must not panic. Your courage, resolution, self – discipline and the endurance have kept you sane, but food, shelter, and the water will keep you breathing. When you are out of the wilderness, be sure to better prepare yourself by always packing equi pment which will make your survival easier on you, and spread the word. Tell others; make sure that they don’t go through what you have just escaped from. Senior Nuts Human beings are born with numerous natural instincts; yet, none is as basic as the instinct of survival. Though many people may never need it, it is an invaluable knowledge given to us by God. Humans are born to live and consequently they are born with the ability to survive. When we talk about ‘survival skills’ we consider ways in which we can fulfill our most urgent needs in any situation. Via many years of societal evolution, we have lost our ability to provide for ourselves if we don’t have access to a store, and have become ignorant on how to survive in the wilderness.If you can find food and water, and you can make fire and shelter, then you can survive in the wilderness. And when it comes time to find your way out of your situation, you will need to know how to navigate without a phone, gps, compass, or map. However, should you find yourself lacking one of these five components; you will not survive, or ecape, unless the void is compensated. It is a simple fact that if you do not eat then you will not live. However, finding food is much more complicated than it seems. The methods for finding and getting hold of wild food in a particular kind of country usually require detailed local knowledge† (Bridge 270). Unfortunately, when in a survival situation detailed knowledge of an area and its edible plants is not always an asset. In addition, it is rare for you to have a fishing pole or any kind of hunting equipment. Thus, you might find yourself literally up the creek without a paddle. However, there are a few ways to find food, and a few well-known plants that are edible. First of all, you must take advantage of your location.It can be difficult to catch animals on land thus you must find edible plants. Among the well-known edible plants are blackberries, black walnuts, cattail, daylily buds, hickory nuts, acorns, and morning glory leaves (Edible). However, it is often difficult to discern these edible plants from their poisonous peers. There is an edibility test you can use when faced with this situation. You must simply take a plant and rub it on a sensitive part of your body, the inside of the wrist for example, and wait fifteen minutes.If there isn't any adverse effect then you should chew a very small amount of the plant for five minutes and see if there is any adverse effect. If, after this, you still feel fine then swallow the plant and wait eight hours. If you are still feeling okay then eat a small handful and wait another eight hours. If nothing happens then it is okay for you to eat the plant sparingly. (Edibility Test) Some other tips for finding edible food include avoiding all plants with white sap, tiny hairs, umbrella shaped flowers and white or green berries.In addition, you should stay away from mushrooms and fungi, plants with bulb roots and fruits from plants with shiny leaves. Aggregate berries such as raspberries are always edible, as are single fruits on a stem. With this information y ou can find food and pass step one of surviving. However, it is very important that if a water source is not available you should not eat because water is required for digestion (Equipped). The second step to surviving is finding, or creating shelter. Exposure to extreme heat or cold can result in death from only three hours of exposure.Consequently, finding a shelter or constructing you out of the resources around you is vital. An example of this is when a married couple and their young child found themselves stranded in a snow bank. Before going out to seek help the man built his wife and child a cave in the snow. Without this cave, the man's family would have almost certainly died (Survival). Regardless of the scenario, a shelter is needed and should be constructed in a safe environment. You should avoid camping in meadows because of the mosquitoes and you should be cautious of animal shelters.Shelters can also be constructed out of tarps, tree branches, and snow. It is unfortuna te that humans have destroyed so much nature because we have made it harder for ourselves to survive by ruining trees, creating paths and destroying natural shelters. â€Å"It is rare than an overhanging rock that serves as a good shelter is even capable of being found these days† (Bridge 174). Perhaps the most important asset for survival is water. It would be a miracle if you survived for more than three days without water and there is no substitute for it. It is imperative that when driven by thirst you do not drink seawater, blood, or urine.These fluids will only hasten dehydration (Survival). In addition, you must know that thirst itself is not good indicator of hydration levels. You can be dehydrated and lack thirst. â€Å"Dark colored urine is the most reliable indication of significant dehydration† (Equipped). There are many ways to find water, but you should not push yourself too far. Rationing sweat is just as important as rationing water. You can find water by collecting dew or melting snow. You should avoid consuming un-melted snow because it lowers your body temperature. Follow animal tracks downhill; they might lead to a watering hole.Also, if you find yourself in an arid area, you should dig to find water. Even in a desert you can find water. Simply dig a hole in the sand, covering and suspending a plastic bag into it and collecting water, which condenses at the bottom of the plastic container. If bad comes to worse, you should not avoid drinking water that might be contaminated. Only do so as a last resort. An intestinal problem is much friendlier when contrasted with death (Equipped). For nearly every situation, fire will be the essence of your survival. Fire is the Swiss-army-knife of wilderness survival. It can play multiple roles.It provides warmth, and comfort, while cooking and preserving food. It also purifies water, signals for help, and provides protection from animals. †It can be a psychological boost by providing peace of mind, and companionship†. (FireCraft) To make a fire, you need to understand the mechanics of fire, and how it works. †Fuel ( in a nongaseous state)does not burn directly. † When heat is applied to the fuel, it creates a gas which, when mixed with air, burns. There are many types of fire structures, which can all be equally successful. The tepee style is the simplest, both to explain and to build.To make a tepee fire, you will arrange a tinder ball and stack small sticks around it in a cone shape. You will light it in the middle, causing the tinder ball to burn which catches the twigs on fire that then fall inward fueling the fire further. Once you are able and willing to escape the wilderness, you will need to figure out which way is north. An easy way of doing so is to create a make-shift compass rose on the ground. You can make this by sticking a leafless branch, which will cast a definite shadow, in the ground and marking the tip of the shadow, which g ives you the west heading.Wait for about fifteen minutes and mark the new point, giving you the east heading. Now stand with the west to your left and east to your right. You are now facing north. When on the move, be sure to leave yourself plenty of daylight to setup camp and to build a fire. With food, water, shelter and fire you can survive in the wilderness. Yet, in order to find these things you must try to maintain a positive mental attitude (Equipped). If you find yourself in a survival situation, you must prioritize: water then shelter then food. Never give up.As easy as giving up might seem when faced with death and lacking hope, you must keep on trying and you must think. Do not waste energy by doing before thinking. You must not panic. Your courage, resolution, self – discipline and the endurance have kept you sane, but food, shelter, and the water will keep you breathing. When you are out of the wilderness, be sure to better prepare yourself by always packing equi pment which will make your survival easier on you, and spread the word. Tell others; make sure that they don’t go through what you have just escaped from.

Friday, August 30, 2019

Coal Keeps the Lights on

He would go in at dark and leave at dark and often go without eating or taking a break because his Job was so demanding. Even though mining was dangerous and vigorous work he loved his Job. In 1966 his pay was $3. 25 an hour, for that day and time he was making good money. In 1980 when he had to quit due to health issues his top pay was $26. 00 an hour. 00nes) fit was hard, but I had a Job to do.Coal keeps the lights on. said Delbert. His Job came with many responsibilities. He had to take care of himself, make sure his workers were all safe and make sure they got the Job done. Cones) When he got his Job finished he was ready to go home to his wife and family. Delbert said there was nothing better than the boss saying may boys lets shut her down, its time to go home. That was something they looked forward to after a long days work. Upchurch 2 He knew when he was a little boy he was going to be a coal miner. His grandfather, father and many close relatives and friends were all coal mi ners.If you lived in Harlan, more than likely you were going to be working in the mines. The best thing he liked about his Job was the challenge of hard work. He said he loved anything that came as challenge to him, he loved when he achieved exactly what he set out to do. Cones) Jones said he misses working in the mines. If his health was better he would be right back. He also said that most of his family worked in the mines, but he wouldn*†° want any of his grandchildren going through what he did to provide for his family. He said It was a good Job, but he could live without the aches and pain he feels veryday.Cones) Although life in the mines were hard, it was even harder on his body. The twenty two years he gave the mines gave him back one destroyed body. He ended up having black lung disease from inhaling all of the coal dust which eventually turned in to COPD Cones) He also nad to go through six back surgeries trom all ot the bending over and crawling he had to do. He said if you work in the mines you will come out with an old tattered up and worn down body. He would love to be living in Harlan, working dusk til dawn living the coal miners life. It was and will always be apart of who he is.Two of his sons also worked in the mines along side of him. They didn*†° put nearly as many years as he did, but put enough in to both be disabled with back injuries. Jones said it was important to him that he see them get out of there before they got *lack lungand It take over the rest of their lives. He said he would have loved it if his body would have let him work long enough to retire from the mines. That was one of the goals he had set for himself that he didn*†° get to accomplish. Jones said he is somewhat thankful he got out when he did, if not the stress of the Job may have been too hard on

Thursday, August 29, 2019

Global Warming : causes, effects and remedies Essay

Global warming is the greatest challenge facing our planet. It is, in fact, the increase in the temperature of the earth’s neon- surface air. It is one of the most current and widely discussed factors. It has far-reaching impact on biodiversity and climatic conditions of the planet. Several current trends clearly demonstrate that global warming is directly impacting on rising sea levels, the melting of ice caps and significant worldwide climate changes. In short, global warming represents a fundamental threat to all living things on earth. Global average temperature rose significantly during the past century. The prevailing scientific view is that most of the temperature increases since mid-20th century has been caused by increases in atmospheric greenhouse gas concentrations produced by human activity. Most scientists agree that planet’s temperature has risen 0.5 degree Celsius since 1900 and will continue to increase at an increasing rate. As a result, the world is getting warmer. The year 1990 was the hottest year in the last century. Together with 1991, the years of 1983, 1987, 1988 and 1989 have been measured to be the warmest six years in the last hundred years. The year 1991 was the second warmest year of the past century. The consequences of the rise in temperature is being felt all over the globe the findings of scientific research done in this field reveal that the temperature of the earth is likely to rise from 1.4 °C to 5.8 °C within a period of 100 years. Unfortunately, the imbalance which we have created between our life and earth is already showing the signs disasters in the form of flood, cyclones, landslides, tsunami, drought, etc. If the imbalance continues to rise, one day this will pose a question mark on the existence of this planet. Carbon dioxide (C02) which is an important constituent of environment is causing a warming effect on the earth’s surface. It increases the evaporation of water into the atmosphere. Since water vapour itself is a greenhouse gas, this causes still more warming. The warming causes more water vapour to be evaporated. The C02 level is expected to rise in future due to ongoing burning of fossil fuels and landuse change. The rate of rise will depend largely on uncertain economic, sociological, technological and natural developments. Other gases such as methane, CFCs, nitrous oxide, tropospheric ozone are also responsible for global warming. Increases in all these gases are due to explosive population growth, increased industrial expansion, technological advancement, deforestation and growing urbanisation, etc. Trees play a significant role in the global carbon cycle. They are the largest land-based mechanism for removing carbon dioxide from the air. Deforestation is checking these positive processes. It is the second principle cause of atmospheric carbon dioxide. Deforestation is responsible for 25 per cent of all carbon emissions entering the atmosphere, by the burning and cutting of 34 million acres of trees each year. Everyday over 5500 acres of rainforest are destroyed. As a consequence of massive loss of forests, global CO, levels rise approximately 0.4 per cent each year, the levels not experienced on this planet for millions of years. As we know the forests are the great absorbers of CO,,. There is a close relation between global warming and population growth. Today the large population on earth is using the technologies which are destructive for the earth. Approximately, 80 per cent of atmospheric C02 increases are due to man’s use of fossil fuels either in the form of coal, gas or oil. A large portion of carbon emission is attributed to the burning of gasoline in internal-combustion engine of vehicles. Vehicles with poor gas mileage contribute the most to global warming. Besides, the sulphur group gas is the most harmful for this. Its contribution is 30 per cent in global warming. This gas is also emitted from the burning of fossil fuels. Increase in global temperatures will cause rise in sea level. It will lead to melting of glaciers, changes in rainfall patterns, increased intensity and frequency of extreme weather. As per the latest survey report the rate of melting of glaciers has seen sharp increase in recent times. Even those glaciers are affected from global warming which have been considered permanent. The shrinking of glaciers is going to pose a major problem of drinking water. The sea levels as a result of melting of glaciers have risen from 0.35 mm to 0.4 mm. Scientists have warned in their reports that most of the glaciers will disappear within a period of 15 to 25 years. It will create problems of drinking water and food grains in most of the North American countries. India is not unaffected from it. The Himalayan glaciers have shrunk about 30 per cent after 1970. The rise in sea levels is a major cause of concern. A large number of cities located in coastal areas will submerge in the sea. Besides, many island countries will ultimately â€Å"lose their existence and will be washed away from the surface of the earth. The damage of rising sea levels is diverse. Buildings and roads close to the water could be flooded and they could suffer damage from hurricanes and tropical storms. Experts believe that global warming could increase the intensity of hurricanes by over 50 per cent. In addition, as the sea rises, beach erosion takes place, particularly on steep banks. Wetlands are lost as the level rises. Rise in atmospheric temperature will lead to the outbreak of air ¬borne and water-borne diseases. It would also contribute to the rise in death caused by heat. The problem of drought would be frequent. Consequently, malnutrition and starvation will pose serious challenge before humanity. Global warming is a great threat to the flora and fauna of the earth. A large number of species of them may become extinct. The expanse of desert would increase. Low rainfall and rising temperature could add to the intensity and frequency of dusty storm. This in turn will immensely affect the quality of agricultural land, ultimately causing adverse effect on agricultural produce. It would have far-reaching socio-economic impact. In Indian context, the impact of global warming is a matter of grave concern. As is well known, India is mainly an agricultural country and agriculture here is gamble of the monsoon, e.g. largely depending on rainfall. Though it is to affect the whole country, the worst likely impact would be on central and northern India which is high-yielding parts of the country. These are the regions which produce the largest agricultural yield. The rise in atmospheric temperature and fall in rain would naturally result in decline in crop production. Moreover, it would have great effect on biodiversity as well. The growing concerns over global temperatures have led to the nations, states, corporations and individuals to draw out a plan of action to avert the situation. As a result the world’s primary international agreement on combating global warming was reached in Kyoto in 1997 which came to be known as Kyoto Protocol. However, ten years have passed; the situation does not appear to be very changed. It seems that the member countries are not very serious about its devastating effects. In addition, forestation can be of great help in this regard. Planting more trees and reducing timber cuts worldwide will help restore the imbalance. Secondly, we must follow on environmental policy of ‘reduce, reuse, recycle’, i.e. promoting the reuse of anything. Thirdly, the use of fuel-efficient vehicles should be promoted as these vehicles have lower emissions of harmful gases. Fourthly, every individual should be aware of the importance of the protecting environment. Besides, eco- friendly technologies must be promoted, and must be substituted with the technologies which cause great emission of global warming gases. Public awareness campaign can be of great help in this regard because unless each and every individual is aware only governments’ effect cannot bring desired difference.

The effectiveness of fiscal policy between the Neo-Keynesian and the Essay

The effectiveness of fiscal policy between the Neo-Keynesian and the Monetarist framework - Essay Example Fiscal policies affect the demand and supply patterns in an economy, if the government imposes heavy taxes on various commodities the consequences are that prices will increase and demand will be low. If such a trend continues, supply will reduce and eventually the company will quit the market if not shift its concern to another line of production and this will result to retrenchment processes and low-income rates to the losers (workers). At the long run, the government will observe a lower G.D.P (gross domestic product) and reduced income per capita (Dwivedi 17). If a government engages in operations that will see it maintain expenditures at a desired level, it will have practiced fiscal policies. The practice is effective through adjustments in taxes, interest rates and the spending styles of the government itself (Musgrave, Frank, & Elia 80). Through the practices, the government either helps the final consumer, but whether this happens as anticipated is dependent on the shifts th at the government employs either to vary rates on increased or decreased edge. The policies show relevance to those of the monetarists. Neo Keynesian theory stipulates that the factors to a progressive economy revolve around demand. The factors are demand itself, produced output and the rate of employment. The theory argues that an economy enjoys stability when the factors are exercised but not to the maximum exploitation of its output. The rate of employment in a country increases income per capita. This stimulates demand since buyers are able to decide and make purchases promptly at their will. Increase in demand will lead to increase in price or supply accordingly. The simultaneous changes in demand and supply factors will result to inflation if the prices increase considerably (Satora and Richard 67). At this point, government intervention becomes a point, and therefore measures must put in place to create harmony among the factors, this is referred to as fiscal policies. In mos t cases, the government will borrow money from the economy by issuing premiums, it may also issue decrees to the lending facilities on a stab to minimize the amount of money in supply, and it may impose taxes and duties over the produce. The practices as well will reduce spending patterns leading to reduced production. Eventually jobs will be lost resulting to economic recession. Monetarists argue that whenever a country revamps money into the economy, chances are that growth is in the short-term, and the ultimate result will be the pressure of inflation. They state that a slight change in government policies will affect the market either positively or negatively and reflect at the short and long runs. It is during inflation that the entire consumer group will cut down on spending since prices are high. The country will face unemployment problem since suppliers will be quitting the markets. Entirely, the country will not pose an attracting site to the investors due to adverse curren cy fluctuations. Understanding that subsequent currency fluctuations will result to devaluation, the country finds itself in a rather bitter position as its currency will affect exportation of goods. Therefore, it will have set an economic sanction to itself

Wednesday, August 28, 2019

Nursing Research Paper Example | Topics and Well Written Essays - 1250 words

Nursing - Research Paper Example Insanity, craziness or madness is a pattern of behaviors which makes people a danger to themselves and others. â€Å"Dorothea Dix played an instrumental role in the founding or expansion of more than 30 hospitals for the treatment of the mentally ill† (I Tell What I Have Seen—The Reports of Asylum Reformer Dorothea Dix, p.624). This paper briefly analyses the history of Dorothea Lynde Dix and her contributions to the society as a social reformer and a dedicated nurse. Dorothea Linde Dix was born on April 4, 1802 in Hampden, Maine. Today the land where Dix’s house stood is called the Dorothea Dix Park (Colman, p.12). When Dorothea was born, Thomas Jefferson was American president and only 16 states were there in America. Maine was not a state at that time. She was grown up first in Worcester, Massachusetts, and then went to Boston at the age of twelve, in order to stay with wealthy grandmother. The major purpose of her journey towards Boston was to escape from her alcoholic and abusive father. Joseph Dix was her father and Mary Bigelow was her mother. The Dix family had two other children also, born after Dorothea. Dorothea’s social activities started at the age of 19. ... She published a small book of facts for schoolteachers during this period which became extremely popular. â€Å"By the time of the Civil War, Conversations on Common Things; or, Guide to Knowledge: With Questions had been reprinted 60 times† (I Tell What I Have Seen—The Reports of Asylum Reformer Dorothea Dix, p.624). This book was written as a conversation between a mother and daughter and she tried to criticize the discrimination in giving education to men and women. Dix failed to get proper education because of the social discrimination existed during her period with respect to the education of the men and women. Only the male community got better education during her period. She has restarted her educational activities in 1831 and opened another model school for the girls. However, she could not continue her activities because of the failure of her health again. She suffered a mental illness during this period and her ill health ended her teaching career which motiv ated her to look for other options of social activities. She went to England in 1836 for better treatment and this journey has shaped her career as a dedicated social reformer. â€Å"Dorothea’s growth and development from a teacher of young ladies to the Samaritan of the mentally afflicted is a fascinating story†(Dorothea Dix, Forgotten Samaritan, p.1441). In England, she got company of a family (William Rathbone family) which engaged in political and social reformation process. Moreover, â€Å"she met prison reformer Elizabeth Fry, and Samuel Tuke, founder of the York Retreat for the mentally ill during this period. (I Tell What I Have Seen—The Reports of Asylum Reformer Dorothea Dix, p.624). Her grandmother’s death

Tuesday, August 27, 2019

History Essay Example | Topics and Well Written Essays - 250 words - 47

History - Essay Example With his power, he ran a strict government that was the first in the form fortified behind the great wall china, which was built by his directive (â€Å"Qin Shi Huangdi: The First Emperor of China†). On the other hand, the leadership of Augustus used integration of power and authority to lead his subject. To conquer the world in his era, Augustus used power where he forced his subjects and conquered nations to fight in order to achieve peace. This was his doctrine, pax romana, that the only way to achieve peace was to assert his power upon the world through military victory (â€Å"Qin Shihuangdi, Caesar Augustus and Jesus†). However, the authoritative phase followed the creation of a new world order that was based on morality and military superiority. From this moral superiority stemmed from commitment to marriage and family thus, he coerced his subject through marriage laws to stamp out immorality (â€Å"Qin Shihuangdi, Caesar Augustus and Jesus†). Through this, both authority and power seem to work for the good of the

Monday, August 26, 2019

Obesity in Kuwait Research Paper Example | Topics and Well Written Essays - 500 words

Obesity in Kuwait - Research Paper Example According to a study conducted by Zaghloul et al. energy intake among Kuwaitis is extremely more than what is actually required for a person. It was higher than the estimated energy requirements for almost half of Kuwaiti children and one-third of adults. The Estimated Average Requirement was exceeded by 78–100 % of the recommendation for protein and carbohydrates. It should be noted that majority of the energy drinks and foods contain excessive sugar and fat contents. Sugar and fat are responsible for causing obesity. These food and drink items are extremely expensive compared to normal food and drink items. Only high income people will be able to spend money for these items. In other words, high income is causing obesity among Kuwaitis. Another reason for obesity among Kuwaitis is the globalization. It should be noted that globalization has brought many life style changes in this world. Because of globalization, it is easy for fast food chains to establish food outlets anywhere in the world. Foreign direct investments are welcomed in almost all the countries because of globalization. As a result of that, global fast food companies such as KFC, McDonalds and Burger King are able to establish food outlets in any country at present. The case of Kuwait is not an exception. Because of globalization, a variety of fast food companies have already established restaurants in Kuwait. According to the arguments in the article â€Å"Is  Globalization  Making Us Fat† Social globalization, have a significant impact on obesity. A social mismatch is there among the people because of globalization. This mismatch results in differences in the energy consumption levels of the people. In other words, physical and cultural e nvironments are key elements behind obesity (Is  Globalization  Making Us Fat?). According to Kumiya et al.,(p.1027) in highland areas worldwide, socioeconomic  globalization  is progressing urbanization. This

Sunday, August 25, 2019

Mortgage and Housing Market Crises Essay Example | Topics and Well Written Essays - 1250 words

Mortgage and Housing Market Crises - Essay Example From the above diagram as the demand for houses increase this shifts the demand curve to the right, this causes the prices to increase as shown above, when demand increase for houses then there will also be an increase in the demand for mortgages. The demand for mortgages increased and as the market bubble got more and more inflated there was a market bubble burst which resulted to low value of houses, this is made it impossible for home buyers to repay their mortgages as the value of their houses declined. As the price of houses rose there was a rise in anticipation that the price in the housing market would still rise, for this reason therefore there was an increase in the level of borrowing in the united states, in this period the rate of borrowing increased four times and this resulted into more and more borrowing which was encouraged by the low interest rate mortgages and the high value return from the housing market, as a result of this the asset bubble rose and when the housing market experienced a bubble burst the prices declined to near zero and investors lost a lot of their value. Increased in demand for mortgages increased the rate of mortgage frauds, many borrowers lied about their income levels which made it easier for them to qualify for mortgages, after the asset bubble burst the result of the mortgage crises that faced the state where people borrowed money to finance for houses but the value of their houses were too low at the time to cover the mortgage. The government: The government is also blamed for its role to this crisis, the government passed the community reinvestment act that stated that allowed borrowing to uncreditworthy customer, further it is also evident that the introduction of this act increased high risk loans to the renders, for this reason therefore it is clear that the mortgage crisis can be blamed to the government for failing to put in place policies that would have governed the housing market. Effects of the crisis: The mortgage crisis affected almost everyone in the economy, the mortgage companies and other lenders lost a lot of finances as a result of this crisis, the housing market companies and mortgage companies performed poorly in the stock market following the crisis compared to other industries. Financial sector employment declined after the crisis, over 30, 000 employees lost their jobs during 2007 to march 2008. From this therefore it is clear that the housing market bubble led to loses in nearly everyone in the country including increased unemployment, poor stock market performance of financial institutions and loss of value of assets. It is however anticipated that the housing market prices will continue to decline until it self adjust. Solving the crisis: There are two

Saturday, August 24, 2019

Early Greek,Roman,and Christian Historiography Essay

Early Greek,Roman,and Christian Historiography - Essay Example To this extent, it is important to note that the writing of pre-modern history, often known as historiography, involved early historiographers writing about various civilizations that existed at their lifetime and even beyond (Bispham, Harrison, & Sparkes, 2006). In this regard, it is worthy to note that some of the major civilizations that the historiographers documented included the early Greek, Roman, and Christian civilizations. Due to the diversity of these civilizations, many historiographers adopted different approaches in pursuing the history of such civilizations (Mehl, 2005). This paper therefore, compares and contrasts the various approaches to the historical inquiry pursued by Greek, Roman, and Christian historians. Essentially, the early Christian Historiography incorporated a number of approaches that were unique to the civilization, as the historiographers at the time (Osborne, 2004). Perhaps it is important to commence by noting that all the Christian Historical materials must bear apocalyptic, universal necessity, and periodical significance, according to the Christian principles (Bispham, Harrison, & Sparkes, 2006).. Certainly, Christian historiographers take the approach of universal necessity in the sense that they attempt to describe the history of the world from the creation of man to the latest events in the Christian history (Marincola, 2010). This means that Christian historiography only goes to the universal extent of seeking the origin of the races and distribution patterns of such races. On the contrary, the Greco-Roman historiographers take a slightly different approach in the sense that it is more particular in describing the history of civilizations (Mehl, 2005). Instead of d escribing how civilizations and powers rose and fell, the Greco-Roman historiographers describe Greece and Rome as the nerve centres of all historical revolution. On the other hand, the Christian

Friday, August 23, 2019

Case Study Example | Topics and Well Written Essays - 1250 words - 5

Case Study Example A firm’s support and analysis of this scenario would reveal that, in the point at which there is a clear distinction between the ‘data’ and the ‘information’ expected from it, the outcome would be the realization of the fact that ‘data’ is nothing but a raw and unorganized collection of facts that need processing in order to make them meaningful and useful. This is a sense that was not being noted in FreshDirect prior to Braddock becoming the CEO; hence, the noted losses in sales, revenue as well as the decline in the customers’ base or numbers (Laudon & Laudon, 2013). Considering this, not unless well organized and put to proper usage, organizational data can be quite useless and meaningless. Therefore, the organization of data so as to produce adequate information would greatly enhance the business cycle and growth of the organization (Wisner, Tan & Leong, 2011). Further still, whereas when the collected data is adequately organized, processed, structured and presented in the required context; thus, making it useful and meaningful, it will be referred to as ‘information.’ In the case of FreshDirect, its business entails dealing with a huge number of customers in a single business day. As such, it would be required to ensure that it accurately takes all their order, delivery time and the locations of delivery. This amount of data is quite huge, and if not sorted out, the likely result would be a total mess and mix-up in orders, delivery and even a cause in delivery times since no proper information is generated to indicate the location of clients so that a truck only serves a region. The success of FreshDirect also required a huge number of human resources for it to run, and a huge amount of data for it to run. Thus, it would make no meaning if the collected data is not enhanced to produce the required information this a failure in the

Thursday, August 22, 2019

Tiffany com Essay Example for Free

Tiffany com Essay In what way(s) is Tiffany exposed to exchange-rate risk subsequent to itsnew distribution agreement with Mitsukoshi? How serious are these risks?Answer: About 15% of (1992) sales of $492mln or ~ $75mln will now be earned inYen, but will have to be reported in $. At a Net Income (1992) of $25mln, the risks caused by this exposure are significant. Data from exhibit 6 shows that ina 6-month period (Apr-Sep) exchange rates fluctuated as much as 10%. (from 133.30  ¥/$ to 120.07  ¥/$). A 10% downward fluctuation like this would translate into a third of a drop in net results ($25mln -/- $75mln x 10%) to . 67mln, assuming everything else stays the same (e.g. all costs incurred in $, prices to consumersremain unchanged).1.In what ways is Tiffany exposed to exchange-rate risk subsequent to its new distribution agreement with Mitsikoshi? How serious are these risks?Tiffany is exposed to foreign exchange risk by selling directly to the Japanesemarket. When they sold wholesale to Mitsukoshi, Mitsukoshi bore all the foreign exchange risk. Under this new agreement Tiffany is now exposed to the volatile fluctuations in the yen-dollar exchange rate. Since Tiffany is making profits in yen they have to convert the yen to dollars to take back to their home country. Since the yen is thought to be overvalued in comparison to the dollar, the future exchange rate can decrease Tiffanys profits. Also, the extreme volatility in the exchange rate creates significant uncertainty in what the future exchange rate and profits will be if left unhedged. The most important foreignexchange risk facing Tiffany is2. Should Tiffany actively manage its yen-dollar exchange-rate risk? Why or why not?Answer: Tiffany should actively manage its  ¥/$ exchange rate risk for the following reasons:1. The possible impact on its result as described in the answer to question 1is significant;2. There are strong indicators (on a PPP-basis the Yen is highly overvalued) that a correction will occur, which might mean even larger exchange-rate fluctuations than have occurred in the past.The way Tiffany manages its  ¥/$ exchange-rate risk is of course a function of how exchange-rate development scenario  s relate to the cost involved in [the instruments used in] managing this

Wednesday, August 21, 2019

My Life had stood - a Loaded Gun Essay Example for Free

My Life had stood a Loaded Gun Essay Emily Dickinson’s â€Å"My Life had stood a Loaded Gun† is a powerful poem that takes into account various thematic expressions. Its comprehensiveness in brevity is another essential feature of this poem. It symbolizes power and unconventional feminist urges on the art of the poetess. In this poem, Emily Dickinson finds an instrument adequate enough to render her need for fulfillment through absolute commitment to love’s service. The poem begins with a brilliant conceit. Fused from the ambiguous abstraction of life and the explicit concretion of loaded gun, it expresses the charged potential of the human being who remains dormant until â€Å"identified† into a conscious vitality. And after hat identification, we observe the start of a new poem i. e. the start of a new life. Historically, it was written in age when American society was torn with civil war. The symbol that Emily Dickenson has used is an essence of an experience. It is quite obvious that a universal insight that the poet tries to express in not obtained merely by imaginative wandering, it is based on concrete experiences. Emily Dickinson presents the same insight into the historical experiences of her time. The very first stanza symbolizes the paradox of finding oneself through losing oneself. It is rendered in the poem by one word: identity is claimed when someone claimed the gun as her own. The American civil war was also the process of finding ones own identity by losing ones own identity. The internal rivalries and petty identities were to be removed to achieve a national reconciliation. This national reconciliation ultimately brought the national identity. Although this process was on halt and stayed â€Å"in corners† for many decades till a day came. Now they â€Å"roam in Sovereign Woods†. So Emily Dickinson has epitomized a national experience. Now this â€Å"gun† is â€Å"foe of His Im deadly foe†. â€Å"His can be described in various connotations. â€Å"His† is emblem of nation state that is fully sovereign. â€Å"His† is an integrated society or the one who longs to be integrated after the pathos and miseries of Civil war. Poetess further emphasize that â€Å"None stir the second time -/ whom I lay a Yellow Eye -/ an emphatic Thumb†. All these gestures are for those who are internal or external antagonists to the new national experience. This poem has also captivated the feminist attention who has given it a new evaluative dimension. Some critics are of the view that thorough this poem, Emily has tried to present a woman that she was not primarily in the second half of the 19th century whereas other feminist critics holds the view that poem totally negates the feminine qualities and the main metaphor considers â€Å"everything [that]woman is not: cruel not pleasant, hard not soft, emphatic not weak, one who kills not one who nurtures. † (Bennet, 1986) But Emily Dickinson has provided a framework of power i. e. feminine power and established certain pattern on which women power can grow and has shown certain direction where women power can direct itself. It must be kept in mind that all the action verbs in the poem are not destructive or of insidious nature. It expresses powers to hunt speak† smile guard and kill. So this power has paradoxical nature and a balance mix of these powers is necessary as shown and done by Emily Dickinson. Furthermore, Miss Dickinson does show a longing for deadliness but in actuality it is only for safeguarding. Wrath is a part of her being but she does not let it go if not invoked or incited. So her aggression and anger and the consequences as a result of it (killing and deaths) are not unwomanly but are an extension of her very personality. These feelings are not uncommon but are surely unpredictable. In the second half of the poem, she is only providing guard to one who has helped her to get rid of her alienation and had blessed her with intimacy. Here Emily Dickinson seems conventional in her feminist approach that a woman can do everything unwomanly for the one who is her companion in true sense of the word. Christine Miller (1987) says in this regard that â€Å"In the second instance, the speaker prefers guarding the master to having shared his pillow, that is, to having shared intimacy with himprimarily sexual, one would guess from the general structure of the poem. † On the other hand, this poem expresses the agonies of a female poet that was restricted by her family and society to a narrow life devoid of any intellectual and/or literary independence. These social and familial compulsion produced rashness in Emily’s attitude. She was forced to produce art in seclusion and to it keep to herself only. So language becomes her only mean and tool to bear the torments of her intellectual beings. She embodies language as gun and is of the view that this loaded gun accompanied with her literary beings is fatal for socio-cultural compulsion against women. It provided her a sense of power and control. She further eulogizes language and considers it a safeguard to her literary being. And her language is enemy to al those traditions, norms, people and things who are against her poetical endeavors. This poem can further illustrate the conflicts between two classes with their interest. Although this conflict is not materialistic or monetary but it exists in the socio-cultural domain. One class adheres to the conventions and does not allow female members to express their view on any issue especially in the form of poetry whereas other lass are comprised of the intellectual beings who consider it their right to create and disseminate their thoughts and ideas in the literary form. This poem symbolizes the struggle of the latter class and demonstrates that they are more powerful than the convention-ridden society. The poem starts with an individual quest for his/her identity but it changed into a capitalized â€Å"We†. Now the concern of the poetess is no more individualistic and sentimental, rather it has been transformed into something collective, societal and concrete. The identities have been mingled up with each other. Both owner and the â€Å"owned† perform the same masculine activities. They are no more individual but become a part of the larger whole i. e. society. Overall the poem captures a variety of themes through various thematic expressions. Although the conclusion is disturbing but it has relevance to the thematic expressions as it tries to resolve the problem initiated in the first half. Powerlessness or even fear of that is death to the poetess has no other option but â€Å"to die† without powerlessness. Last stanza is not a moralistic commentary but is identification of a wider truth. Bennett, Paula. My Life a Loaded Gun: Dickinson, Plath, Rich, and Female Creativity. Boston: Beacon Press. 1986. Gilbert, Sandra M Gubar, Susan. The madwoman in the attic: the woman writer and the nineteenth-century literary imagination. New Haven: Yale University Press. 1979. Miller, Christanne. Emily Dickinson, a poets grammar. Cambridge, Mass. : Harvard University Press. 1987. Smith, Martha Nell Loeffelholz, Mary. A companion to Emily Dickinson. Malden, MA: Blackwell Pubishers. 2008.

Side Effects of Tumor Size Reducing Drugs | Experiment

Side Effects of Tumor Size Reducing Drugs | Experiment Manish Kumar Tiwari 1. Introduction: Objective: Pfizer have developed a new drug that appears to reduce the size of specific tumors but are concerned about what effect the drug might have on normal tissue. Outline how you would use DNA technology to address this issue. Cancer disease has large complexities in terms of genome variations at genetic level and epigenetic level. Immortalization and tumor genesis are the two fundamental characteristics of cancerous cells. This disease is caused by mutations in genes such as oncogenes, DNA repairing genes and tumor suppressor genes. Recent researches suggested that more than one mutations are needed for the cancers. One of the major drawbacks of the medicines or drugs that are used to treat cancer is its side effects on normal cells. The cells which are mostly affected by drugs are rapidly dividing cells such as blood cells, hair follicles cells, cells found in tract of reproductive organ and digestive system, and cells from immune system. Side effects on normal cells due to chemotherapy has become major challenges for researchers. Transcriptome or protein expression profiling for cancerous cells treated with specific drugs may provide useful information about possible side effects on normal cells. When a ny drugs or medicines are given for the treatment of any specific tumor disease, it binds with specific receptors (cell surface receptors, Cytoplasmic receptors or nuclear receptors) and leads to transcription and translation process and generate specific proteins that can be able to stop the cell cycle or initiation of apoptosis. But generally these drugs may also responsible to translation of unwanted proteins that can cause side effects on normal tissues. 2. Approach: Mode of action of many drugs that reduces the size of tumor are related to growth cycle (like mutagen, MAP kinase pathway) or DNA modifications (transcription, translation etc.). This method is more suitable for in vivo testing in rats or mammalian cancerous cell lines which has been described here. The added tumor size reducing drug must bind with specific receptors on the tumor cells. So first step is the identification of pathway via which it acts. In the downstream signaling of the pathway, some transcription factors will be activated and will bind to target promoter and reduces the size of tumor. So then transcription factors need to be quantified by qPCR as well as the sequence of their promoter through DNA Foot Printing. Now two plasmids need to be constructed (minimum two plasmids, if there are more transcription factors and promoters, more plasmids with different fluorescent proteins are needed) containing above identified promoter coupled with red fluorescent protein (RFP) and containing a tumor inducible promoter coupled with green fluorescent protein (GFP). Now for in vivo testing, mutant mouse are created and transfected with above two plasmids. During the growth, the known tumor inducing compounds/radiation is given to the mouse to induce the tumor. As the drug is added, it will cause induction of RFP through the body but level may be higher in tumor cells but GFP should be induced only in the tumor cells. If GFP is induced in other normal cells it means that this drug may cause side effect on that cells. A fluorescent mapping of mouse will reveal the efficacy and side effects of drug based on RFP and GFP intensity.  Ã‚   Figure 1: Schematic presentation of approach. The image of mice is taken from internet which has been used to explain the method. 3. Method: This method is suitable for in vivo testing in mice or mammalian cells culture. The main steps include quantification and identification of transcription factors and promoter sequences respectively, construction of suitable plasmids coupled with red and green fluorescent proteins, transfection of plasmids in mice body, tumor induction in mice body followed by drug injection and last fluorescent mapping using fluorescent detector. The instruments and techniques which will be used in this methods are qRT-PCR, DNase Foot Printing assay, Suitable plasmids vector, microinjections, Chemicals, fluorescent proteins (red and green), capillary electrophoresis, tumor inducing cells or chemicals or radiation and fluorescent detector. Validation of this method is important so validation could be possible by using this method for any known drug which side effects on normal cells has been identified completely. 3.1. Quantification of Transcription Factor: The exact quantification of transcription factor is the most important part of this method. Micro array or PCR is the good technique for quantification of transcription factors but in this method qPCR/QRT-PCR will be appropriate technique. First step is isolation of cancer cells from mammalian cancerous cell lines. Then inject target anti-cancer drug and incubate for some time because these drugs takes some time to start their function. After proper incubation, total or poly A RNA extraction is the next step. The solution which is used in extraction process should be RNase free otherwise it can degrade our RNA so that exact quantification could not be possible. Sample should be treated with DNase to remove genomic DNA contamination. Flow Chart 1: Steps involved in quantification of Transcription factors Electrophoresis and qPCR methods could be used for determination of purity and accurate concentration because these factors are very important for proper gene expression profiling. Then C DNA synthesis and validation of C DNA quality and quantity could be done by using qRT-PCR. For performing qRT-PCR assay there are two important steps such as selection of appropriate reference genes and designing of PCR primer labeled with fluorescent dye must be needed. For data analysis fluorescent detector can be used to detect transcription factors and their associated genes. Now once genes have been identified by using above method so the identification of their promoter sequence DNA Foot Printing assay will be performed. 3.2. Identification of Promoter Sequence: DNase Foot printing assay method can be used to identify target promoter sequence. Steps involved in this method is amplification of target DNA through PCR using fluorescent labeled primer at 5’ end. Then cleavage of the amplified DNA by using DNase enzyme followed by the capillary electrophoresis. The cleavage pattern will vary due to the presence of transcription factor, because the binding sites are protected by the protein from the cleavage. By using this method we can identify the promoter sequences. By using capillary electrophoresis we can identify the amount and size of DNA fragments and about the bases which are not cleaved by the DNase enzyme. Figure 2: Identification of promoter sequences through DNA Foot Printing assay. The graph between amount and size of DNA fragments in this figure is showing the bases which are protected by the transcription factor against DNase enzyme. 3.3. Construction of Suitable Plasmids: Construction of suitable expression vectors for mammalian cells, that can carry the desired promoter sequence coupled with fluorescent protein must be needed. The most important characteristics of vectors is presence of all elements that is suitable for expression in host cells. The important elements are promoter, stop and start codon, binding sites for ribosome, ORI region and appropriate selection markers. Some examples of vectors like adenoviral, PSV and pCMV are generally used for expression in mammalian cells. In this method, our expression vectors should contain promoter sequence labeled with red and green fluorescent protein and other important elements. Minimum two type of plasmid vectors need to be constructed. One plasmid should have promoter coupled with RFP which has not induced by the tumor inducible transcription factors. Other plasmid should have tumor inducible promoter coupled with green fluorescent protein. Our main idea is to inject these vectors into the mutated mice body so that we also need to remove the other elements of vectors that can cause any unwanted diseases in mutated mice. The vectors like pED and Pz can be used for the expression in mammalian cells. Figure 3: Construction of plasmids containing promoter coupled with Red and Green fluorescent protein. The very first step for the construction of the recombinant plasmid is the cleavage of both plasmid and target DNA with promoter sequence coupled with fluorescent protein using suitable restriction enzymes. The restriction enzymes creates sticky or blunt ends (depends on type of restriction enzyme used) in both plasmid and target DNA. Next step is the hybridization of both DNA and plasmid using DNA ligase enzyme. Selection of cells having plasmid with desired sequence is very important so further we need to selection of appropriate vector by using selection markers like antibiotic resistance genes. 3.4. Transfection: The transfer of desired plasmid inside the mice body could be possible through many ways such as microinjection, electroporation, shotgun method, through chemicals and viral infections. Transfection through viral infection has some limitations like limited carrying capacity of desired gene and unwanted inflammatory mutations. However, transfection through viral infection have some advantages like easy to handle, easy preparation and easily monitoring during the process. So, in this method transfection of plasmid in mice should be done directly through microinjection into the mice body. One another way for transfection of recombinant plasmids in mice is through recombinant Baculovirus. Baculovirus infects insect cells. Purified budded virus can be isolate from the infected insect cells with recombinant Baculovirus. This purified budded virus can be introduced inside the mice body. For the study of side effects on normal cells in whole body of mice it is very important that this recomb inant plasmids will reach every parts of body along with tumor affected parts. 3.5. Induction of Tumor in Mice: Mammalian cancerous cell lines or cell DNA extracted from virally infected cells can be able to induce cancer in mice. Once theses tumorgenic cells is injected inside the mice body it develop specific tumor. After developing cancer in mice body, anti-cancer drug is administered through injection to show the efficacy and side effects on cancerous and non-tumor cells. When drugs binds with specific target receptors, it will induce both promoters but with varying intensity. The promoter coupled with RFP will show intensities in both normal and tumor cells but may be higher in tumor cells. But GFP should be induced only in tumor cells if it is inducing in other normal cells with high intensity then it may cause side effects on those normal cells. 3.6. Fluorescent Mapping: Analysis of fluorescent mapping of these promoters in different locations of the mice body can provide useful information about possible side effects against designed anti-cancer drugs. For example if GFP will be induced in other cells like hair cells, heart cells, bone marrow cells than we can predict the side effects on these cells because the drug should not induce translational process in normal cells. If this drug induces promoters only in tumor cells then the chances of side effects may be less. We can study possible side effects against various drugs by using this method. Figure 4: This picture has been modified for illustrating the possible results that can be produced by this method. Region B and C in this figure are representing the cancerous cells where GFP has been expressed. Region A is representing the normal cells where GFP has been also expressed so this drug may cause side effects on this cells. 3.7. Validation of the Method: This approach has not been validated because this is the hypothesis only. For the testing of this method whether it is working efficiently or not need to be validated. An efficient approach has been described here. For the validation of this method we need to perform this method on known anti-cancer drugs for specific type of cancers. This method can be apply for known drugs which side effects on normal cells have been identified completely. If fluorescent mapping provide exact location in the body where GFP has been induced and if these locations are related with those areas where this specific drug causes side effects then this method will be validated. But proper validation need to be tested for various anti-tumor drugs which side effects has been completely known. 4. Discussion: There are so many side effects associated with anti-cancer drugs because these drugs mainly affects rapidly dividing cells and immune system. The drugs or medicines that are currently used have always some common side effects like typhlitis, diarrhea and hair loss but sometimes these drugs cause serious side effects like liver damage and cardiac arrest because these drugs are unable to differentiate rapidly growing normal and cancerous cells. So that development of proper efficient method for testing possible side effects for any anti-cancer drugs should be developed. In this section a good approach has been described for the identification of possible side effects on normal cells. The idea is based on the role of transcription factors induced by the drug- receptors interactions. As instance certain anti-tumor drugs causes anemia when used for the treatment of specific tumor. Generally the gene called HBB is responsible for anemia because this gene encode beta globins protein. It mea ns that these drugs also induces transcription factor that is responsible for activation of HBB gene. The fluorescent mapping of unknown anti-cancer drug against specific cancer can provides useful information about possible side effects. The figure 4 which has been modified to illustrate the possible results that can be achieved through this method. If the drug is not inducing GFP in normal cells except cancerous cells it means drug will not cause any side effects on normal cells but vice versa if GFP is expressing in other cells along with tumor cells so we can predict possible side effects on those cells because this method is also useful to find out what type of protein or transcription factors are expressed. By using bioinformatics data bases like PDB, Gene bank etc, functions of expressed proteins or transcription factors can be easily predict. The method which has been described above has not validate yet because this method is only a hypothesis that need further advancement and validation. 5. References: Lohmann, S., Herold, A., Bergauer, T., Belousov, A., Betzl, G., Demario, M., Dietrich, M., Luistro, L., Poignà ©e-Heger, M., Schostack, K., Simcox, M., Walch, H., Yin, X., Zhong, H. and Weisser, M. (2013). Gene expression analysis in biomarker research and early drug development using function tested reverse transcription quantitative real-time PCR assays. Methods, 59(1), pp.10-19. Swartzman, E., Shannon, M., Lieu, P., Chen, S., Mooney, C., Wei, E., Kuykendall, J., Tan, R., Settineri, T., Egry, L. and Ruff, D. (2010). Expanding applications of protein analysis using proximity ligation and qPCR. Methods, 50(4), pp.S23-S26. Genetics Home Reference, (2014). HBB gene. [online] Available at: http://ghr.nlm.nih.gov/gene/HBB [Accessed 23 Nov. 2014]. Dubensky, T., Campbell, B. and Villarreal, L. (1984). Direct transfection of viral and plasmid DNA into the liver or spleen of mice. Proceedings of the National Academy of Sciences, 81(23), pp.7529-7533. Caldana, C., Scheible, W., Mueller-Roeber, B. and Ruzicic, S. (2007). A quantitative RT-PCR platform for high-throughput expression profiling of 2500 rice transcription factors. Plant Methods, 3(1), p.7. Kim, T. and Eberwine, J. (2010). Mammalian cell transfection: the present and the future. Analytical and Bioanalytical Chemistry, 397(8), pp.3173-3178.

Tuesday, August 20, 2019

lighthod Voyage into the Darkness in Joseph Conrads Heart of Darkness :: Heart Darkness essays

Voyage into the Heart of Darkness The voyage into the "Heart of Darkness" is told to us through the eyes of Charlie Marlow. As Marlow is aboard the "Nellie" he tells his story of expedition and growth. The men on the boat sit still yet bored. Marlow is like an old man sharing a story of his childhood, that for himself may be of great significance, and lead to a lesson, but the children yearn to hear a story of magic, castles and sword fights. Joseph Conrad uses Marlow's character to get across and express his own opinion. The story Marlow shares with the other men, is a story of reflection. It is a mirror, like most experiences are. Experiences in our lives that teach us and reveal something in our lives that had to be fixed. In this case Marlow (or Conrad) uses Africa as the mirror into the hearts of early Europeans that wished to colonize and only help profit the "less unfortunate". What was it exactly that this unchartered land had in store for Marlow? As Marlow tells his story we see and understand the situations Marlow faced. In his first encounter with the tribes men, Marlow steps into a "gloomy circle of some inferno", where dark figures surrounded him. He compares this incident with that of a massacre, the starving and wasting bodies lying in "confusion". Marlow then encounters a young black boy with a piece of white cotton string tied around his neck. This simple piece of string symbolizes the young boy's innocence. Shortly after Marlow offers the boy a biscuit, another one of the shapes approaches the river , crawling, and drinks of the water. Marlow could not stand the sight of the suffering any longer. It was as though he felt what they were feeling and just when he was willing to help, he stands up and walks away. The path where Marlow meets those that had traveled to an unknown land, and walked uncertain of where they where but sure of what they wanted, started here. The patchwork young man ,( the Russian) is the only one in the jungle without an interest in gaining something out of the jungle, except for his own "breathing space". His devotion for Kurtz is an admiration out of ignorance and perhaps even innocence. Through the Russian Marlow learns a great deal about who Kurtz really is.

Monday, August 19, 2019

Variation in the Punishment of Hate Crimes Essay -- Law Legal Crime Re

Variation in the Punishment of Hate Crimes Love Thy Neighbor. We have all been taught, if not have heard these same words. There are two opposite words in the dictionary with two opposite meanings. Love is defined as to have a deep, tender, ineffable feeling of affection and solicitude toward a person, and on the other side Hate is told as to feel hostility or animosity toward a person or thing. With this, hate crimes can be murder or assault, or racially or religiously motivated. In the following cases you will see that hate crimes take many different forms and there exists a wide variation among states in the specifics of their laws.   Ã‚  Ã‚  Ã‚  Ã‚  In the Mississippi Code punishment for Hate Crimes are noted in 99-19-301 through 99-19-307. In order to impose an enhanced penalty under the provision of 99-19-301 through 99-19-307, the jury must find beyond a reasonable doubt: that the defendant knew that the victim was within the class delineated; and that the defendant had specific intent to commit the offense because the victim was within the class delineated. As subsection two of the hate-crimes statute indicates, in order for the felony enhancement to apply, a person must commit an underlying misdemeanor â€Å"primary offense.† Primary offenses under the statute include assault, property destruction, criminal trespass, and any misdemeanor offense against public order and decency. According to the Mississippi crime and punishment graph, hate crimes that are any felony or misdemeanor act racially motivated may double in sentence.   Ã‚  Ã‚  Ã‚  Ã‚  Beckwith v. State, Medgar Evers, a black civil rights activist and leader in the turbulent 1950s-1960s civil rights struggles, was murdered at his home in Jackson January 12, 1963. Byron De La Beckwith, a vocal prosegregationist and white supremacist in this State, was arrested June 23rd and indicted for Evers’ murder at the July, 1963, term of the grand jury of Hinds County. He stood trial in February, 1964, and following a hung jury, a mistrial was ordered by the circuit judge February 7. He again stood trial in April, and following another hung jury, the circuit judge declared a mistrial April 17, 1964. Until his second trial, Beckwith had been incarcerated without bail. Following his second trial Beckwith was released on $10,000 bail. He ran a markedly unsuccessful election and his successor on March 10, 1969, moved court t... ... duty, the criminal justice community must have adequate information about the nature and prevalence of hate crimes.† The Statistics shoe that the top two places for hate crimes to take place are in the street/alley and at a residence. In a 2002 statistic Mississippi was shown to have four total offenses, two in aggravated assault and two in intimidation. Mississippi standards are that the punishment may be doubled in any felony or misdemeanor act racially motivated. My opinion may be that any act resulting in death from a hate crime act should be sentenced to life to death in prison. Hate crimes can be murder or assault, or racially or religiously motivated. These cases prove the difference the people and the crime committed. â€Å"Erase the Hate.† Works Cited Ward v. Utah, March 10, 2003, 321 F. 3d 1263 Beckwith v. State, December 22, 1997, 707 So. 2d 547 James Bryd Jr., Berry v. State, July 27, 2001, Tex. App. – Beaumont, 2001. Not reported in S.W. 3d. State v. Ladue, July 01, 1993, 631 A. 2d 236 http://dir.yahoo.com/Society_and_Culture/Crime/Types_of_Crime/Hate_Crimes/ http://www.fbi.gov/ucr/hatecrime2002.pdf http://www.cnn.com/US/9904/05/gay.attack.trail.02/

Sunday, August 18, 2019

Gudea statues Essay -- essays research papers fc

Discovery of Statues in Lagash Lagash was one of the oldest cities in Sumer and Babylonia. Today it is represented by a long line of ruin mounds, which are rather low, now known as Tello al-Hiba in Iraq. Located northwest of the junction of the Euphrates and Tigris rivers, and east of the ancient city of Uruk, it is positioned on the dry bed of an ancient canal, approximately 10 miles north of the modern town of Shatra.# The ruins of Lagash were discovered in 1877 by Ernest de Sarzec, a Frenchman, who was allowed by the Montefich chief, Nasir Pasha, to excavate the site at his pleasure in the territories under the governing of Nasir Pasha. Ernest de Sarzec continued excavations at this site with various interludes, at first on his own account and later as a representative of the French government, until his death in 1901. The smaller mounds had apparently been comprised mostly of storage houses, in which vessels, weapons, sculptures, and other objects that were used by the administration of palace and temple. However, the primary excavations were made in two larger mounds, which later were found to be the site of the temple known as E-Ninnu, a shrine to the patron god of Lagash, Nin-girsu. The temple had long been destroyed and a fortification was built on what remained of the temple, during the Seleucid period. It was underneath this fortification that numerous statues of Gudea were discovered, which make up the heart of the Babylonian collection at the Louvre Museum#. Overall the statues had been damaged, some decapitated and others broken in various ways, having been put into the foundation of the new fortification. Also in this section came a mixture of fragments of basic artifacts including various objects made from bronze and stone, of high artistic excellence. Some of these objects have been dated to the earliest Sumerian period enabling historians to trace Babylonian art and it’s history to a date some hundreds years prior. Excavations in the other mound resulted in the uncovering of the remains of various buildings. In these outlying buildings de Sarzec discovered about thirty thousand inscribed clay tablets, the record archives of the temple. The tablets contained the business records, the nature of its property, the methods used to cultivate the land, methods on herding its animals, and its commercial and industrial dealings. The ancie... ... A shaped frame. Works cited: Cooper, Jerrold. Reviews of Gudea and His Dynasty by Dietz Otto Edzard. The Journal of the American Oriental Society, Vol. 119, No. 4. (Oct-Dec 1999): pg 699-701. Edzard, Dietz Otto. Gudea and His Dynasty. Toronto: University of Toronto Press, 1997. Hallo, William W. and Simpson, William Kelly. The Ancient Near East: A History. New York: Harcourt Brace Jovanovich Inc., 1971. Hansen, Donald P. “New Votive Plaques from Nippur,'; in the Journal of Near Eastern Studies, Vol. 22, No. 3. (Jul., 1963). pg 145-166. Howorth, Henry H. “The Later Rulers of Shirpurla or Lagash,'; in The English Historical Review, Vol. 17, No. 66. pg. 209-234. England, 1902 Olmstead, A. T. “The Babylonian Empire,'; in the American Journal of Semitic Languages and Literatures, Vol. 35, No. 2 (Jan., 1919). pg 65-100 Unknown. “A photogrammatic study of three Gudea statues,'; in The Journal of the American Oriental Society. pg 660. 1990 Encyclopedia.org Lagash. Louvre Museum. Seated statue of Gudea, prince of Lagash. UMBC of Maryland. Gudea and the Kritios Boy Wikipedia. Lagash. WorldHistory.com. Gudea and Statues of Gudea.

Saturday, August 17, 2019

Poem Blessing, by Imtiaz Dharker

The poem blessing, by imtiaz dharker depicts the desperation of water in a place which is a victim of drought. the poet has very vividly described the unfortunate situation and has also made the reader sympathize greatly with the poverty sticken people of this area. The poet begins the poem with a simile â€Å"the skin cracks like a pod† which appeals to the visual imagery of the reader as it paints a picture of people with very dry skin in the readers mind.This simile is used very effectively as it not only adds to the visual imagery of the reader but also captivates the reader by hinting to the reader about the lack of water in an area which is further described in more detail. the next line clearly states the theme of the poem which is the description of a situation with deficiency of water and extreme poverty. In the former part of the poem ,† imagine the drip of it†, the poet is expressing the desperation of water by the people. this line is being said or thou ght by the people affected by this calamity! t suggests that these people are craving water so much that they are hallucinating about the sound of water splashing into a tin mug and comparing this sound to â€Å"the voice of a kindly god†. the words† small splash† and â€Å"echo† add to the auditory imagery of the reader which help the reader understand the situation being expressed by he poet more vividly. the writer mention a â€Å"tin mug† in the hallucination of the victims which suggests poverty to the reader . this is because while dreaming about water which is heavenly for these people they imagine it being dripping Into a tin mug which is unusual in financially supported households.Moving on the poet uses a metaphor comparing water to fortune in the line†the sudden rush of fortune†. this metaphor enhances the language used and also emphasizes on water being demanded highly and hence being called â€Å"fortune†. The poet the n describes a scenario where a municipal pipe bursts and water is leaking in abundance. another metaphor is used here comparing water to silver. this comparison once again emphasizes on the high demand and craving for water. This scenario is described vividly in the lines â€Å"roar of tongues†¦Ã¢â‚¬ ¦Ã¢â‚¬ ¦frantic hands†.These lines add to the visual imagery of the reader and help the reader grasp a more detailed picture trying to be painted by the poet in the readers mind. the word â€Å"frantic† is used to emphasize on the emergency of the situation. In the latter half of the poem the poet mentions â€Å"naked children screaming† being present in the situation . this line puts a poverty stricken atmosphere forth to the reader and makes the reader feel sympathetic towards the situation. in the last stanza the poet has mentioned the presence of heat significantly in the lines† liquid sun†,†polished to perfection† and â€Å"flashin g light†. hese phrases repeatedly remind the reader about the scorching heat which adds to the misery of the situation.The poem ends leaving a significant impact on the reader with the element of god coming in. the poet mentions that angel rays,†flashing light†, shine over these people suffering which signifies that god is watching over their â€Å"small bones†. this phrase also adds to the visual imagery of the reader portraying a scenario effected by poverty and hunger. The poem is written in free verse . njambments llike â€Å"echo in a tin mug†,†every man woman child for streets† and â€Å"frantic hands and naked children† are present in abundance which adds to the flow of the poem due to no rhyme scheme being present. According to me this poem was very appealing as it made me respect the luxuries I get and take for granted. the poet has been able to describe the helpness situation of these poor and hungry people so vivdly that it made me nderstand the value for the goods and services these poor people don’t benefit from and also feel greatly sympathetic towards them.

Friday, August 16, 2019

Principles of Macroeconomics Essay

Topic: Tolstoy’s narrator remarks that Ivan Ilych’s life has been â€Å"most simple and most ordinary and therefore most terrible† (731). Explain how the events of Ivan’s life support this assessment. What is terrible about the ordinary? There are many milestones in one’s life. Graduating college, getting a job, getting married, buying a house and having kids. For most people these are joyous events that are celebrated with family and friends; and come with hard work. However some people have a different mindset towards life. They perform tasks for the mere sake of getting the job done and life almost seems like a check list. There is a difference between being alive and truly living. Being alive is fulfilling the responsibilities and duties that are required of you. Truly living is when you seize every moment and make the most of it. One appreciates the small pleasures in life and is satisfied with what he or she has. It is easy to go through life without realizing you are not enjoying it. We get so caught up in trying to be the best version of ourselves that we don’t stop and appreciate the small things that bring every day joy. In â€Å"The Death of Ivan Ilych† Leo Tolstoy examines the life of a man, Ivan, who would have seemed to live a typical life with adequate wealth, high position, and family. However as we read on we come to realize that he is living almost robotically. Relationships don’t have much value in his life. He does what he thinks is the right thing to do, and follows the examples of everyone around him. He is scared of getting left behind and wants to make a name for himself. This leads to Ivan Ilych’s life being â€Å"most simple and most ordinary and therefore most terrible† (1458). His life ends up being a total waste with no real friends, no happiness and lots of regret. It is not until Ivan is on his death bed in his final moments  that he realizes that the personal relationships we forge are more important in life than who we are or what we own. But by then it’s too late. Today’s society is very fast paced; everyone is always on the go. People think about the big picture and miss the small details of life. This is a very common mistake in the western culture. All working people want to follow the script of life, but th ere are some extremists like Ivan that take it to the next level. With every aspect in his life he wants to be perfect and will do anything to achieve and maintain his status. An example of his extreme behavior is his love life. Ivan was at a point in his life where he settled down in a new town and life was pleasant. There â€Å"he met his future wife, Praskovya Fedorovana Mikhel, who was the most attractive, clever and brilliant girl of the set in which he moved† (1461). He establishes a light relation with her; and slowly she falls in love with him. Ivan had no intension of marrying her, he thinks of his marriage primarily in terms of himself. He thinks of marrying her only because she had all the qualities that he thinks a good wife is supposed to have; she came from a good family, was good looking, had an income and â€Å"it [marriage] was considered the right thing by most highly placed of his associates† (1461). So Ivan gets married; it doesn’t sound like he is madly in love with her. It’s more like he marries her because other people tell him it’s a good thing to do and he doesn’t have any objections. For I van other people’s approval and views matter more than his own views. Marriage is one of the most important and joyous events in one’s life; most  people get married when they think is the right time for them and with whom they think is the right person, however for Ivan it’s just another task on the checklist. In other words Ivan got married just for the sake of getting married. There was no joy or excitement; he makes marriage look like a simple and ordinary event in one’s life. Relationships are easy to make but hard to maintain. As Ivan’s married life goes on he realizes that marriage is not as easy and pleasant as he thought. As things started to change in his life, he felt depressed and helpless. He wants to escape and live life his own way, invite friends over for a game of cards and go to the club in the evenings. On the other hand his wife wanted him to spend more time with her and there was nothing wrong with that, it is expected. Every wife wants  her husband to spend time with her especially while she’s pregnant. However for Ivan his work is more attractive because it brings him success and that’s what’s most important to him. He doesn’t understand the importance of family and ignores his wife; Ivan spends more time at work and becomes more ambitious than before. Money is an essential need in life and it is a man’s responsibility to provide his family with all the comforts of life, since the men are usually the breadwinners of the household. However if you pay too much attention to money it can damage your relationship with your family because you lose out on time with them. Relationships with family have a much larger effect on quality of life than money does. However Ivan fails to realize this and concentrations totally on work, it is not until he’s on his death bed that he understands the importance of family in life but by then it’s too late. Going back into his childhood it is clear that Ivan was just what â€Å"he remained for the rest of his life: a capable, cheerful, good-natured, and sociable man† (1459). Everyone has someone or the other who they look up to and follow in life. Ivan was attached to people of high position, therefore established friendly relations with them. He took their blueprint of life which consisted to wealth and social status; and blindly followed it. Ivan did all the things they did, even though he didn’t like what he was doing. He was disgusted with himself and regarded everything he did to be wrong but because all these things were done by people with good position, it did not matter (1459). Childhood is the best part for most people; they do what they want, don’t care about others and most importantly have fun. However Ivan got so caught up in being the best version of himself, he missed all these cheerful things. He did what he thought to be the right things, which were the things done by successful people. It is not bad to follow successful people, everyone should do that however not to the extent that Ivan did. He did not listen to his heart or brain. He even chose his friends on the base of their social status and not whether he liked them or not. If something seemed wrong to him, he tried to forget it only because it was regarded right by the people with good position. There wasn’t anything special about his childhood, he basically followed a script. After law school Ivan’s life is pleasant; he performs his job and makes his career in the province. Later  in his life he takes up the post of examining magistrate in a new town (1460). His social life picks up where it left off. Ivan â€Å"picked out the best circle of legal gentlemen and wealthy gentry living in the town † (1461) to associate with. Here’s another example where Ivan does something because it seems the right thing to do. He wanted to be recognized in society and be powerful so he establishes relationships with rich and powerful people. It didn’t matter if he liked them or not. The relationships he developed with them were on the surface and were just a show, compared to normal friendships that last forever. These men did not have any meaning in his life and vice versa; this is proven when he passed away and his friends care more about their promotions rather than being sad on a loss of a friend. People always compare their lifestyles and what they have to their friends and people around them. It’s a non-ending cycle of always wanting what you don’t have. Ivan was never content with what he had, and it was evident in his life choices. After working as an examining magistrate for a while â€Å"he was expecting to be offered the post of a presiding judge in a University town† (1463). Instead to his horror a colleague got the post. In response to this he quit his job. He began actively hunting for a better position and succeeded. His friend helped him land a position that was two times better than his old one. He was thrilled that he proved his colleagues wrong who failed to appreciate him. It is evident that he was more excited to show off his new position to his â€Å"enemies† than to be genuinely happy about being able to provide more for his kids and wife. We should always take a moment to step back and enjoy what they have before life makes us realize it’s too late. With Ivan’s new job came more money. This led to a bigger and better lifestyle. He bought a grand house and furnished it with expensive pieces. Slowly his dream of having everything he could ever dream of was coming true. He had obtained the status he always wanted, purchased all the expensive things and was slowly getting satisfied with everything. As he settled in to the new lifestyle he always wanted; he quickly became bored. It wasn’t as great as he thought it would be. All throughout his life he always looked at the big picture. He was so concentrated on getting his dream job, house and lif estyle that he didn’t enjoy and appreciate the small pleasures that came along the way. He sacrificed all the small joys of life for the end result and now that it was time for Ivan to enjoy the results of  his hard work, life took a turn in the opposite direction. As he was setting up his new house, he injured himself while putting up curtains. As time went on his injury got worse, and he was never able to fully enjoy the things he had worked for. Ivan’s life had no special moments, as he never understood the joy in small achievements. He took them as simple and ordinary things. As we examine Ivan’s life it is clear to us that it was a total failure as most of the time he was lonely and didn’t have any friends or family he confided his worries to. He never paid attention to his relationships and did not make an effort towards them. As his Injury gets worse it begins to take a toll on his life, forcing him to stay at home. Now that he is at home all the time he begins thinking of his life and starts reflecting on it. Slowly everything hits him. All the mistakes he made are becoming visible to him from his childhood to his relationship with his wife to his job. He is realizing he spent his whole life chasing what he thought would make him a happy man and that he really wasn’t happy at all. He did not establish any friendships at a young age, and the ones that he did were not real, they were on the surface. His life is flashing before his eyes. The empty feeling he had his whole life is turning into regret. As he thinks about his mistakes he realizes that he intended to live life in a certain way, but ended up living in a completely different manner. Like everyone else Ivan didn’t realize this while he was  making these mistakes. He wasted his life running after wealth and status; and failed to build real relationships. In reality he didn’t achieve anything in life other than tangible objects. We as the reader saw these opportunities for him to change throughout his life. As a child Ivan didn’t like what he was doing. He was disgusted with the things he did to become one of the high positioned people. He could have understood that this is not the right way to live life but he was so determined to achieve his goal he turned wrong things into right in his eyes. Later on in his life after he got married, his wife showed frustration towards him, she wasn’t happy with the way of his lifestyle. Most people care about their close ones and try to change for them, whereas Ivan ran away from the situation and started working more and spending less time with his family. He did the opposite of what a normal person would do. Instead of listening to his heart and brain  he changed his morals; instead of strengthening his relations he neglected them. His life choices were ordinary; it seemed like he was just being alive and not truly living. Normally when people die, they are remembered for all the memories and great things they did. Their loved ones grieve over the loss of a friend and family member. A person leaves a legacy after passing away. Many want that legacy to be one of the good times and the memories spent with people you love. However Ivan was unsuccessful in doing that. He was so obsessed with being successful while he was alive it was evident his friends were friends with him for all the wrong reason. After receiving the news of their friend Ivan’s death the first thought of each of his friends was of the changes and promotions it might occasion among  themselves or their acquaintances (1453). Instead of being sad, his friends thought of the benefits they’d get. This shows the type of friendship he had established with his friends. Not only had his friends, his wife too thought about the benefits of his death. Her main concern was â€Å"how she could obtain a grant of money from the government on the occasion of her husband’s death (1457). This was a result of Ivan’s behavior and lack of love towards her. She was a good and loving person; but over time marriage changed her. While Ivan was alive he didn’t treat her with love or give her the place of a wife in his life. Ivan’s wife’s and friends’ behavior give a perfect picture of how he lived his life. He just fulfilled his responsibilities just for the sake of getting them done. Ivan was ordinary in the sense that he had no friends or loved ones. For an outsider looking in on his life he had it all; a big house, nice car, wife, kids and respectable job. However life is not about the tangible objects; houses and cars are just materials but life has a bigger meaning than that. At the end of the day if all the objects were to be taken away from him he has no relationships to hold onto. Life always boils down to the relationships we have, our loved ones and the happiness of our families. It is unfortunate that Ivan realized this when it was too late and he couldn’t do anything about it. Hence his life was â€Å"most simple and most ordinary and therefore most terrible†. Ivan’s misunderstanding of the things that truly mattered in life is what made his life so terrible. Love, respect, intimacy, and happiness are the things that really make life worth living not wealth, power, and property.

Race vs. Ethnicity Essay

If we were to go out on the streets today and ask â€Å"what is the difference between race and ethnicity?†, most people would probably answer â€Å"I don’t know† or â€Å" They are the same thing†. One of the most confused concepts of defining one another is the distinguishing of race and ethnicity. In the past, people either thought one was the other or there was simply no difference. Labeling people in the world is often done without proper knowledge and can lead to making a false accusation or offending someone. Race is associated with one’s biological ancestors, such as your physical appearance. While ethnicity is the identity with people who share similar cultural tradition. Ethnicity and race are different in many ways but are still often confused by many people today. For one thing ethnicity deals with one’s cultural background while race deals with a more genetic background. Geographers study where and why of ethnicity and its locations. Geographers also study where and why people of different races live where they are. Another difference between the two is that ethnicity isn’t as easy to tell by just looking at someone. But if you looked at someone to determine their race you could just tell by their skin color. Say you put a Caucasian male from Canada, Germany, America, and Ireland together in a line; it would be very difficult to distinguish which one from which. But you can easily determine that all the males are Caucasian. Ethnic groups typically seek to define themselves by their language, traditions, and religion; while race is usually defined by skin color. Defining people through race usually leads to prejudice and racism, the belief of one’s race is of superiority than all the others. It is preferred by most people to be identified through their ethnicity, since it represents their culture and doesn’t have the potential to be offensive. In conclusion, race and ethnicity are distinctly different yet are confused among most people of the world. Race is determined by skin color and physical attributes passed down from ancestors. Ethnicity is identifying with your cultural background including language, religion, and traditions. It is better to identify people through their ethnicities instead of their race to avoid offense. Most people do not know the difference between the two or think they are the same. Ethnicity and race connect in a way with each other, but they are and will always be distinct to one another.